Immune Pharmaceuticals Announces Presentation at The Liver Meeting 2017

Poster demonstrates activity of anti-eotaxin-1 antibodies in an animal model of immune-mediated hepatitis

Immune Pharmaceuticals, Inc. (NASDAQ: IMNP) a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, today announced that the results of a study investigating the therapeutic effect of oral and parenteral administration of anti-eotaxin-1 antibodies in an animal model of immune-mediated hepatitis will be presented at The Liver Meeting 2017 - the 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) taking place October 20-24, 2017 in Washington, DC.  Dr. Yaron Ilan, Professor of Medicine, and Director, Department of Medicine at Hebrew University's Hadassah Hospital in Jerusalem, Israel, and an Immune Pharmaceuticals collaborator, will present the data in a poster.

The poster (#350), entitled "Oral administration of anti-eotaxin-1 monoclonal antibody is biologically active in the gut and alleviates immune-mediated hepatitis: A novel personalized therapy for immune-associated liver diseases" (#350) will be presented Friday, October 20 between 12:00 and 1:30 PM ET at the "Autoimmune and Cholestatic Liver Disease" session. The study aimed to evaluate the biological activity and immunomodulatory effect of oral and parenteral administration of anti-eotaxin-1 antibodies in the concanavalin A (ConA) mouse model of immune hepatitis. Anti-eotaxin-1 antibodies, administered two hours prior to the induction of hepatitis, lowered eotaxin-1 levels and prevented the development of hepatitis compared to controls.

Dr. Ilan commented, "These experiments showed that blocking eotaxin-1 can have a profound impact on the development of hepatic inflammation. Anti-eotaxin-1 antibodies lowered eotaxin-1 levels and were effective at blocking liver injury whether administered parenterally or orally.  These results have obvious implications for the potential use of bertilimumab in liver diseases in which chronic inflammation plays a role, including NASH."

Elliot Maza, President and Chief Executive Officer of Immune Pharmaceuticals, stated, "Our collaboration with Dr. Ilan has been fruitful and yielded results suggesting that blocking eotaxin-1 can have a beneficial effect in liver diseases.  We will continue to explore the development of bertilimumab in liver diseases, further to our strategic business plan of focusing our resources on this first-in-class antibody."

Englewood Cliffs, NJ, October 11, 2017

For further information, contact: investors@immunepharma.com

About Immune Pharmaceuticals
Immune Pharmaceuticals is a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases.  Our lead program, bertilimumab, is a first-in-class, fully human monoclonal antibody that targets and lowers levels of eotaxin-1, a chemokine that plays a role in immune responses and attracts eosinophils to the site of inflammation. By neutralizing eotaxin-1, bertilimumab may prevent the migration of eosinophils and other cells, thus helping to relieve associated inflammatory conditions. Currently, we are conducting two phase 2 clinical trials to test bertilimumab in patients suffering from bullous pemphigoid and ulcerative colitis, respectively. Bertilimumab may have application in other diseases, including NASH, atopic dermatitis, immune and inflammatory hepatitis, and asthma.

Safe Harbor Statements Regarding Forward Looking Statements
The statements in this news release made by representatives of Immune Pharmaceuticals, Inc. relating to matters that are not historical facts, including without limitation, those regarding future performance or financial results, the timing or potential outcomes of research collaborations or clinical trials, any market that might develop for any of Immune's product candidates and the sufficiency of Immune's cash and other capital resources, the continued development by Immune of bertilimumab or its determination to seek Orphan Drug designation for the pharmaceutical product of bertilimumab are forward-looking statements that involve risks and uncertainties, including, but not limited to, the likelihood that actual performance or results could materially differ, that future research will prove successful, the likelihood that any product in the research pipeline will receive regulatory approval in the United States or abroad, or Immune's ability to fund such efforts with or without partners. Immune undertakes no obligation to update any of these statements. In addition, there can be no assurance that the Company will ever successfully complete its anticipated corporate restructuring, or that the Company will be able to reduce expenses, capitalize on strategic alternatives, develop its assets, and generate value for shareholders. The Company may, at any time and for any reason until the proposed spin-off is complete, abandon the spin-off or modify its terms and conditions, or consider competing, alternate or complimentary transactions or offers by third parties at the discretion of Immune's board of directors. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as to the date hereof. Accordingly, any forward-looking statements should be read in conjunction with the additional risks and uncertainties detailed in Immune's filings with the Securities and Exchange Commission, including those discussed in Immune's Annual Report on Form 10-K, Quarterly Reports on Form 10-Q periodic reports filed on Form 8-K.

SOURCE Immune Pharmaceuticals Inc.

Immune Pharmaceuticals Appoints John Zhang, MD, PhD as Vice President, Research and Development

 Englewood Cliffs, NJ, USA - December 11, 2017 - Immune Pharmaceuticals Inc. (NASDAQ First North: IMNP) (the "Company"), a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, announced today that it has appointed John Zhang, MD, PhD to the position of Vice President, Research and Development. Dr. Zhang will have oversight of the non-clinical aspects of the Company's drug development programs, incuding all pre- clinical studies, and will provide support for the clinical, regulatory and manufacturing activities for the Company's core pipeline assets, bertilimumab and nano-cyclosporin. Dr. Zhang joins the Company from Tesaro, Inc., Boston, MA, where he served as Director, Clinical Sciences since April 2016, and Director, Toxicology and Safety Pharmacology from Sept 2012 to March 2016.


Immune Provides Corporate Update Regarding NASDAQ US Listing Status

Immune Pharmaceuticals Inc. (NASDAQ First North: IMNP; the "Company") announced today that on December 1, 2017, the Company received a letter from the Listing Qualifications Department of The NASDAQ Stock Market LLC ("NASDAQ") in the United States notifying the Company that the Company's common stock did not maintain a minimum closing bid price of $1.00 per share for the preceding 30 consecutive business days as required by NASDAQ Listing Rule 5550(a)(2) (the "Minimum Bid Price Requirement"). The notice has no immediate effect on the listing or trading of the Company's common stock and the common stock will continue to trade on The NASDAQ Capital Market and NASDAQ First North Stockholm under the symbol "IMNP" at this time.


Immune Provides Corporate Update Regarding Executive Officers

Englewood Cliffs, New Jersey, USA - December 4, 2017 - Immune Pharmaceuticals Inc. (NASDAQ First North: IMNP; the "Company") announced today that effective December 1, 2017, the Company entered into an employment agreement with Elliot Maza, the Company's chief executive officer ("CEO") and the Company's Board of Directors also appointed him to the additional positions of President, Principal Financial Officer and Secretary, until such time as a new Principal Financial Officer may be retained. Mr. Maza was appointed permanent CEO in September 2017, after serving in this capacity on an interim basis since April 2017 and as a Director since January 2015.


Immune Provides Update Regarding NASDAQ US Listing and Departure of Officer

Immune Pharmaceuticals Inc. (the "Company") announced today the public disclosure of certain information regarding its continued listing on NASDAQ US and the departure of its VP Finance.


Immune Pharmaceuticals Publishes Interim Report for the Third Quarter (July-September 2017) and Provides a Corporate Update

Englewood Cliffs, NJ - November 15, 2017 - Immune Pharmaceuticals Inc. (NASDAQ First North Stockholm: IMNP) ("Immune") a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, today announced financial results for the quarter ending September 30, 2017 and provided a corporate update.

Financial Results, July - September:

  • The Company recorded no revenue for the period
  • Research and development expenses were $1.2 million 
  • General and administrative expenses were $1.6 million
  • Loss from operations for the period was $2.8 million
  • Non-operating expenses, consisting of interest expense, gain or loss on changes in fair value of derivative instruments, liquidated damages on notes and loss from extinguishment of debt, were $3.2 million
  • Net loss for the period was $6.05 million
  • Net loss per ordinary share amounted to $0.53

Financial Results, January - September:

  • The Company recorded no revenue for the period
  • Research and development expenses were $3.7 million
  • General and administrative expenses were $ 4.6 million
  • Loss from operations for the period was $8.3 million
  • Non-operating expenses, consisting of interest expense, gain or loss on changes in fair value of derivative instruments, liquidated damages on notes and loss from extinguishment of debt, were $6.4 million
  • Net loss for the period was $14.7 million
  • Net loss per ordinary share amounted to $1.47

We had approximately $76,000 in cash as of September 30, 2017. We realized approximately $16 million in net proceeds from the October 23 public offering.


Immune Provides a Compliance Plan to Nasdaq First North to Satisfy EU Market Abuse Regulations and the First North Rulebook

Englewood Cliffs, New Jersey, USA - November 13, 2017 - Immune Pharmaceuticals Inc. (the "Company") has provided a compliance plan (the "Compliance Plan") to Nasdaq First North (the "Exchange") to satisfy EU Market Abuse Regulations ("MAR"), which applies to companies with securities admitted to trading in the EU, and applicable admission requirements as set out in First North Nordic Rulebook (the "Rulebook").


Immune Pharmaceuticals Inc. Announces Closing of $18,000,000 Public Offering of Convertible Preferred Stock and Warrants

Immune Pharmaceuticals Inc. ("Immune") (NASDAQ: IMNP) a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, today announced the closing of its previously announced public offering of units for gross proceeds of $18,000,000, which excludes underwriting discounts and commissions and offering expenses payable by Immune.


Immune Provides Additional Financial Information in Response to Nasdaq First North Stockholm

Immune Pharmaceuticals Inc. (the "Company") announced today the public disclosure of certain information regarding its current financial position.


Immune Provides Financial Information in Response to Nasdaq First North Stockholm

Immune Pharmaceuticals Inc. (the "Company") announced today that on October 19, 2017, Nasdaq First North Stockholm (the "Exchange") halted trading in the Company's shares pending the Company's providing public disclosure in Sweden regarding its current financial position.


Immune Pharmaceuticals Inc. announces pricing of $18,000,000 public offering of convertible preferred stock and warrants

ENGLEWOOD CLIFFS, N.J., (BUSINESS WIRE) - Immune Pharmaceuticals Inc. ("Immune") (NASDAQ: IMNP) a biopharmaceutical company developing novel therapeutic agents for the treatment of immunologic and inflammatory diseases, today announced the pricing of an underwritten public offering of units for gross proceeds of $18,000,000, which excludes underwriting discounts and commissions and offering expenses payable by Immune.


Följ oss

Om beQuoted

beQuoted publicerar nyheter, analyser och pressmeddelanden för investerare och journalister. Viktiga företagshändelser bevakas av vår egen nyhetsredaktion och vidaredistribueras i ledande finansiella medier.

Vi uppdaterar även nyhetsrum, Investor Relations och IR-webbplatser för företag som vill utveckla sina relationer med finansmarknaden.

Kontakta oss

beQuoted AB
Sturegatan 32
114 36 Stockholm

08-692 21 90
Kontaktformulär

Kontakta oss

Vill du veta mer om beQuoted och våra tjänster så fyll i nedanstånde uppgifter och tryck skicka.

En av våra rådgivare kontaktar dig inom kort.

Namn: Telefon: E-postadress: Meddelande: